Marco is married to a gorgeous woman, has a child and a great job. Everything seems perfect, at least until his wife of 25 years announces that she has another man and wants a separation. Marco is forced to leave home.
Andrea, Maurizio and Sergio are professional idlers, lazy, indolent and full of inventiveness. Maurizio is engaged to the policewoman Anna, of whom he is extremely jealous, Sergio still lives with his mother and Andrea is tyrannized by his wife and his brother-in-law, a former boxer. When a crew arrives in town to shoot a commercial, Andrea and Sergio meet two actresses; in the meantime, Maurizio is dumped by Anna. The three spend a large sum of money on a scratch card to travel to Sardinia in search of the actresses in the commercial.
Five friends who form the "inseparables" group spend an evening having a gargantuan dinner. Returning home, one of them has a heart attack and dies. Soon, however, other friends of the group are also found dead under mysterious circumstances. The journalist Olimpo Lupo of "Resto del Carlino", tasked with following the case, soon becomes passionate about it and turns into a detective.
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